Elsa dan Clive, dua ilmuwan pembangkang yang melakukan eksperimen berbahaya, menggabungkan DNA manusia dan hewan untuk membentuk spesies baru. Dinamakan Dren, makhluk ini berkembang dengan cepat dari bayi wanita menjadi makhluk bersayap yang berbahaya. Makhluk ini membentuk hubungan dengan Elsa dan Clive yang menciptakannya, yang malah jadi berbuntut mematikan.

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Reviews:

"The outstanding creature effects by Howard Berger only get more astonishing as Splice splits into an eerie horror picture, then divides again into something out of Rosemary's Baby"- Lisa Schwarzbaum, Entertainment Weekly

"A powerfully brazen re-telling of an oft-told tale, but in this case ... it still works alarmingly well"- FEARnet

"Splice went down smooth, with its sleek surfaces, terrific special effects and disturbing sexiness"- Salon.com

http://www.splicethefilm.com/

Directed by: Vincenzo Natali
Cast: Adrien Brody, Sarah Polley, Delphine Chanéac, Brandon McGibbon, David Hewlett, Simona Maicanescu
Duration: 104 min